Can B6 Help Epileptics Who Struggle to Control Their Seizures?
This small, but exciting, study suggests that if your epilepsy medication is failing to control your seizures, the missing ingredient may be B6.
Vitamin B6 plays a crucial role in the conversion of the epilepsy encouraging neurotransmitter glutamate into the epilepsy inhibiting neurotransmitter GABA.
B6 has been shown to stop seizures in rare and difficult to treat pyridoxine (B6)-dependent epilepsy in infants. There are also case reports of B6 managing seizures in adults who are anti-seizure medication resistant.
So, researcher set out to see if there is a relationship between levels of B6 and seizure control in adults with epilepsy.
The 30 people in the study were classified as either well-controlled or poorly-controlled, depending on whether they were still experiencing seizures despite their medication. Of the 10 who were poorly-controlled, 60% of them were low in B6; of the 20 who were well-controlled, only 15% were B6 deficient. B6 levels were 35.8 in the well-controlled group but only 17.5 in the poorly controlled group. Analysis of the data revealed that there was a significant relationship between low B6 and poorly-controlled seizures.
This study suggests that the difference between your medication managing your epileptic seizures and not managing your epileptic seizures may be your level of B6.
Cureus. 2022 Jun;14(6):e25669
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