Saffron & the Important Side Effects of Diabetes.

The problem with diabetes is that it doesn’t stop with diabetes. It can lead to important complications like cardiovascular, kidney and liver disease. This meta-analysis set out to see if saffron can help.

This meta-analysis included 13 controlled studies of 840 people with pre-diabetes or diabetes. It used many different forms of saffron.

The results showed no benefit for kidney function, but the news was good from then on.

When it came to the diabetes itself, saffron significantly reduced fasting blood glucose levels compared to placebo.

When it came to liver function, there was no effect on ALT but a significant reduction of AST compared to placebo. Interestingly, another recent meta-analysis of diabetic and nondiabetic people found significant reductions in ALT but not AST.

When it came to cardiovascular disease, saffron significantly reduced systolic blood pressure.

This meta-analysis suggests that, in addition to helping diabetes, saffron can help with some of the important complications of diabetes, including liver function and high blood pressure.

Prostaglandins Other Lipid Mediat. March 2025;177:106949.

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