Huge Study Demonstrates Spirulina’s Benefits for Cardiovascular Health

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Cardiovascular disease is the leading cause of death in the world. One of the tiniest supplements in nature could help the largest health problem in the world.

Cardiovascular disease includes coronary artery disease, angina, stroke, heart attack and congestive heart failure. Important risk factors include high blood pressure, cholesterol problems, diabetes, unhealthy diet and lifestyle, smoking, excessive alcohol, inflammation, oxidative stress and obesity. Importantly, these are, too a large extent, within our control. And, according to the American Heart Association, the fundamental goal in preventing cardiovascular disease is reducing these risk factors.

Spirulina, a blue-green microalgae, has the power to address many of these risk factors. This meta-analysis set out to see just how well it can do it.

The meta-analysis included 35 controlled studies published between 2000 and 2024. Combined, the studies included 1,523 people.

The results showed that spirulina significantly lowered triglycerides, total cholesterol and the unhealthy LDL cholesterol while raising the healthy HDL cholesterol. It significantly lowered both systolic and diastolic blood pressure.

Spirulina also significantly reduced fasting blood glucose, insulin and insulin resistance.

Both weight and body mass index were significantly improved by spirulina.

Markers of inflammation, including TNF-α, IL-6 and C-reactive protein, were all significantly reduced.

If you look back at the risk factors that need to be controlled, you’ll notice that spirulina controls almost all of them. Add that spirulina is powerfully antioxidant and loaded in nutrients, including being a complete protein that is rich in essential fatty acids; vitamins, including B12; and minerals, and it looks like a perfect fit for preventing cardiovascular disease. Importantly, spirulina is also safe.

Complementary Therapies in Medicine. November 2025;94:103242.

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For much more on preventing and treating cardiovascular disease naturally, see our book The Family Naturopathic Encyclopedia.

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The Natural Path is intended for educational purposes only and is in no way intended for self-diagnosis or self-treatment. For health problems, consult a qualified health practitioner for a comprehensive program.

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