Blood Clots: the Pain of Aspirin; the Promise of Pycnogenol
Aspirin is still commonly recommended as a blood thinner for preventing cardiovascular disease despite the lack of evidence that it does. But that’s only the beginning of the problem. Because, though Aspirin is not helping many people, it’s hurting a lot of people. A recent study suggests that, for some conditions, pine bark extract (Pycnogenol) is a far superior option. . . .
Recent research has clearly pointed out that Aspirin does not prevent cardiovascular disease but does singnificantly increase the danger of hemorrhaging. Aspirin is well-known to cause ulceration and gastrointestinal bleeding. A meta-analysis of controlled studies clearly showed that Aspirin is associated with a significant increase in risk of gastrointestinal bleeding and that even taking a low dose does not reduce this risk: there is no safe dose of Aspirin (BMJ 2000;321:1183-7). An incredible 28% of people taking low-dose Aspirin for the prevention of heart disease develop an ulcer (Alimentary Pharmacology & Therapeutics 2005;22:795-801). That’s an incredible statistic: more than a quarter of the thousands of people following their doctor’s recommendation to take Aspirin develop an ulcer.
But what else can you do? There are several safe, natural alternatives, like Ginkgo biloba, omega-3 essential fatty acids, bromelain, ginger, garlic, cayenne, B6 and niacin.
A new study compared Aspirin to pinebark extract (Pycnogenol) in people with retinal vein thrombosis. A thrombosis is a blood clot, and blood clots in retinal veins are common in people with high blood pressure, atherosclerosis and diabetes.
The study asked people who had had one episode of retinal vein thrombosis to follow either standard management, standard management plus 100mg a day of Aspirin or standard management plus 100mg a day of pinebark extract. 17.39% of the standard management group had a recurrence of blood clots. 15.38% of the Aspirin group did. But only 3.5% of the pinebark extract group had a recurrence of their blood clots. The pinebark group also had superior vision.
Importantly, given the risks of Aspirin, the pinebark extract was not only way more effective as a blood thinner for preventing blood clots, it was also safer. The researchers said that their study “indicates that Pycnogenol® seems to reduce the recurrence of RVT without side effects. It does not induce new hemorrhagic episodes that may be theoretically linked to the use of Aspirin® (or other antiplatelets).”
Panminerva Med 2015;57:121-5
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