vitamin C reduces risk of death from COVID-19

A just published study adds to the evidence that vitamin C may play an important role in fighting COVID-19.

The authors of this new study point out that the exaggerated inflammatory reaction known as th cytokine storm is the main cause of acute respiratory distress syndrome and multiple organ failure in people with COVID. They then point out that “Several studies suggested that high-dose vitamin C reduced inflammatory reaction associated with sepsis and acute respiratory distress syndrome.” So, they set out to determine if vitamin C could help people with COVID.

The study included 76 people hospitalized with COVID: 30 of them received standard therapy; 46 of them received high-dose intravenous vitamin C. The dose of vitamin C was 6g twice a day on the first day and 6g once a day for the next four days.

At the end of 28 days, significantly fewer people had died in the vitamin C group. In the control group, 5 of 30 had died, but in the vitamin C group, only one of 46 had died. The vitamin C “remarkably” reduced inflammation and oxygen support status improved more in the vitamin C group. The vitamin C was safe: there were fewer adverse events in the vitamin C group than in the standard care group.

The researchers say that this “study found that high-dose vitamin C could significantly decrease mortality with COVID-19 as compared with standard therapy, so vitamin C may be an effective drug for COVID-19, especially for severe and critical cases.”

A previous published study also found reduced mortality for COVID-19. This study found a nearly 50% reduction in the risk of dying if you were on high-dose IV vitamin C. . While 36% of people on the placebo died, only 19% on vitamin C died. Among the most critically ill, 50% of the placebo group died versus 18% in the vitamin C group (Pulmonology 2020;doi:10.21203/rs.3.rs-52778/v2).



Aging 2021 Feb 26;13(5):7020-34


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