curcumin improves negative symptoms of schizophrenia

Schizophrenia is difficult to treat. Drugs may offer some help to the positive symptoms like hallucinations and delusions, but they are helpless against the negative social and cognitive symptoms like apathy, lack of emotion, poor social functioning and disorganized thoughts. But where the drugs don’t help, a herb might.

To see if curcumin could widen the treatment to include the negative symptoms of schizophrenia, researchers added either a placebo or 3g of curcumin a day to the antipsychotic drugs of 38 people with chronic schizophrenia in a double-blind study.

At the end of the six month study, there was a significantly better response in the curcumin group on the Positive and Negative Symptoms Scale (PANSS) and on the negative symptoms subscale. There was no difference between groups on the positive symptom subscale.

The researchers call these results “promising” because they suggest a safe, effective, natural way of addressing the previously resistant negative symptoms of schizophrenia.

Several other natural supplements have shown promise for schizophrenia, including B3, folic acid, tryptophan, NAC, L-theanine, alpha-lipoic acid, ashwagandha and Ginkgo biloba. For a full discussion of these natural treatments for schizophrenia, see Vol.22, No. 7 of The Natural Path newsletter.


Clin Neuropharmacol 2019;42(4):117-122


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For comprehensive help with schizophrenia, make an appointment to see Linda Woolven now. Can't make it in to the clinic? Linda's clinic now offers virtual appointments.


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 is intended for educational purposes only and is in no way intended for self-diagnosis or self-treatment. For health problems, consult a qualified health practitioner for a comprehensive program.

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