vitamin B12 improves fibromyalgia

Fibromyalgia is a painful condition that interferes with quality of life and is difficult to manage. New research has revealed that a common vitamin can help: a lot.

Fibromyalgia is a common condition characterized by generalized body pain, cognitive and mood disturbances, sleep problems and fatigue. The pain experienced by people with fibromyalgia may be caused by an imbalance of neurotransmitters that excite or inhibit pain, leading to increased sensitivity to pain.

Recent research is suggesting that vitamin B12 may play a role as a pain killer. And it may be able to help normalize the balance of pain sensitizing and numbing neurotransmitters. So, maybe it could help fibromyalgia.

To find out, researchers gave 28 women with fibromyalgia 1,000mcg of sublingual B12 every day for 50 days in an uncontrolled study. This study may be the first to look at B12 for fibromyalgia.

Revised Fibromyalgia Impact Questionnaire (FIQR) scores improved significantly when the women took the B12. The FIQR measures symptom severity and disease impact. The B12 also significantly improved anxiety but not depression. There were no side effects.

This study shows, perhaps for the first time, that B12 safely leads to statistically and clinically significant improvement in people struggling with fibromyalgia.


BMC Rheumatol. 2022;6:51


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