vitamin D and probiotics improve physical and psychological symptoms of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is one of the most common gynecological problems, and it is the most common cause of ovulatory infertility. Though little known and never discussed, PCOS can create mental health disorders. Even less discussed is that there’s help: safe, simple, natural help.

In our just released Vol. 22, No. 5 of The Natural Path, we did a feature article on PCOS. One of the supplements we discussed was vitamin D because deficiency of vitamin D is common in women with PCOS. A small study found that 50,000IU of vitamin D once or twice a week combined with calcium could normalize menstrual cycles and help women become pregnant (Steroids 1999;430-5). Another study found that when women with PCOS were given 20,000IU of vitamin D a week for 6 months, 50% of the women who suffered from menstrual irregularities improved and a quarter of those hoping to become pregnant succeeded (J Endocrinol Invest 2011;34(10):757-63).

Now there’s a new reason for women with PCOS to give vitamin D a try. The mental health aspects of PCOS are little discussed but quite real. But when 60 women with PCOS took 50,000IU vitamin D every two weeks combined with probiotics in a 12 week double-blind study, they improved both physically and psychologically.

The women on the vitamin D and probiotics had significantly greater improvement on the Beck Depression Inventory than women on the placebo. They also had significantly greater improvement in anxiety, stress and general health.

Their physical symptoms also improved more. Markers of inflammation dropped significantly, while markers of antioxidant capacity rose significantly. Excessive facial hair (hirsutism) was also significantly reduced. Most importantly, testosterone levels were significantly reduced.

This exciting study suggests that vitamin D taken with probiotics—which may increase vitamin D levels and enhance vitamin D receptors--can not only make women with PCOS better, it can also, importantly, make them feel better.

For more little known help for PCOS, check out this and this.


J Ovarian Res 2019;12(1):5


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For much more on preventing and treating PCOS, see our book The Family Naturopathic Encyclopedia.

For comprehensive help with PCOS, make an appointment to see Linda Woolven now.


The Natural Path
 is intended for educational purposes only and is in no way intended for self-diagnosis or self-treatment. For health problems, consult a qualified health practitioner for a comprehensive program.

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