saffron effective for depression and anxiety

Recently, we did a comprehensive review of the clinical research on saffron in the herbal journal HerbalGram (the PDF is on the About Linda & Ted page). In that review, we looked at several studies that demonstrated that saffron is a highly effective treatment for depression. Now a new study has not only added to that evidence, but has also shown for the first time that saffron is also an effective treatment for anxiety. . . .


This study was double-blinded and placebo-controlled. 54 people with both mild to moderate depression and anxiety, according to the Beck Inventory, were given either a placebo or 100mg of saffron each day for 12 weeks.

The saffron group had significantly greater improvement in depression than the placebo group with a 2 point greater improvement. The significant improvement in depression is consistent with earlier studies. What is new and exciting about this study is that the saffron group also had a significantly greater improvement in anxiety: the improvement was 3 points better than the placebo group. To our knowledge, this is the first study to show that saffron has antianxiety powers.


J Complement Integr Med 2016;13(2):195-199


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The Natural Path is intended for educational purposes only and is in no way intended for self-diagnosis or self-treatment. For health problems, consult a qualified health practitioner for a comprehensive program.

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